After opening, how long is an Orgain ready-to-drink shake safe to drink? June 20, 2022 23:24 Updated Orgain ready-to-drink shakes should be consumed within 2 hours of opening if they are not refrigerated. After opening and if refrigerated, the Orgain ready-to-drink shake should be consumed within 72 hours. Related articles What is the shelf life and how should I store the Orgain ready-to-drink shakes? Does Orgain use milk or dairy? What is the shelf life and how should I store the Orgain protein powder? How do I reset my password or update my login details? What are Shop Pay Installments?