After opening, how long is the protein powder safe to consume? August 20, 2020 22:51 Updated If open and stored in a cool, dry place the product will have a shelf life through the date on the bottom of the canister. Related articles What is the shelf life of Orgain protein powder? After mixing powder with liquid, how long is the mixed shake or smoothie safe to drink? Do your products contain all 9 essential amino acids and is it a complete protein? What is the shelf life of Orgain ready-to-drink shakes? How should I store the Orgain ready-to-drink shakes?