After opening, how long is the protein powder safe to consume? August 20, 2020 22:51 Updated If open and stored in a cool, dry place the product will have a shelf life through the date on the bottom of the canister. Related articles What is the shelf life of Orgain ready-to-drink shakes? What is the shelf life of Orgain protein powder? Are your ingredients tested for heavy metals? How should I store the Orgain protein powder? After mixing powder with liquid, how long is the mixed shake or smoothie safe to drink?